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3PBL

Structure of the human dopamine D3 receptor in complex with eticlopride

Summary for 3PBL
Entry DOI10.2210/pdb3pbl/pdb
Related PRD IDPRD_900001
DescriptorD(3) dopamine receptor, Lysozyme chimera, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, 3-chloro-5-ethyl-N-{[(2S)-1-ethylpyrrolidin-2-yl]methyl}-6-hydroxy-2-methoxybenzamide (3 entities in total)
Functional Keywordsstructural genomics, psi-2, psi-biology, protein structure initiative, accelerated technologies center for gene to 3d structure, atcg3d, 7tm, g protein-coupled receptor, gpcr, gpcr network, signal transduction, hydrolase, eticlopride, dopamine, neurotransmitter, chimera, t4l fusion, membrane protein, transmembrane, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceHomo sapiens (human, Bacteriophage T4)
More
Total number of polymer chains2
Total formula weight108672.38
Authors
Primary citationChien, E.Y.,Liu, W.,Zhao, Q.,Katritch, V.,Han, G.W.,Hanson, M.A.,Shi, L.,Newman, A.H.,Javitch, J.A.,Cherezov, V.,Stevens, R.C.
Structure of the human dopamine d3 receptor in complex with a d2/d3 selective antagonist.
Science, 330:1091-1095, 2010
Cited by
PubMed: 21097933
DOI: 10.1126/science.1197410
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.89 Å)
Structure validation

217705

数据于2024-03-27公开中

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