3PBL
Structure of the human dopamine D3 receptor in complex with eticlopride
Summary for 3PBL
Entry DOI | 10.2210/pdb3pbl/pdb |
Related PRD ID | PRD_900001 |
Descriptor | D(3) dopamine receptor, Lysozyme chimera, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, 3-chloro-5-ethyl-N-{[(2S)-1-ethylpyrrolidin-2-yl]methyl}-6-hydroxy-2-methoxybenzamide (3 entities in total) |
Functional Keywords | structural genomics, psi-2, psi-biology, protein structure initiative, accelerated technologies center for gene to 3d structure, atcg3d, 7tm, g protein-coupled receptor, gpcr, gpcr network, signal transduction, hydrolase, eticlopride, dopamine, neurotransmitter, chimera, t4l fusion, membrane protein, transmembrane, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human, Bacteriophage T4) More |
Total number of polymer chains | 2 |
Total formula weight | 108672.38 |
Authors | Chien, E.Y.T.,Liu, W.,Han, G.W.,Katritch, V.,Zhao, Q.,Cherezov, V.,Stevens, R.C.,Accelerated Technologies Center for Gene to 3D Structure (ATCG3D),GPCR Network (GPCR) (deposition date: 2010-10-20, release date: 2010-11-03, Last modification date: 2023-09-06) |
Primary citation | Chien, E.Y.,Liu, W.,Zhao, Q.,Katritch, V.,Han, G.W.,Hanson, M.A.,Shi, L.,Newman, A.H.,Javitch, J.A.,Cherezov, V.,Stevens, R.C. Structure of the human dopamine d3 receptor in complex with a d2/d3 selective antagonist. Science, 330:1091-1095, 2010 Cited by PubMed: 21097933DOI: 10.1126/science.1197410 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.89 Å) |
Structure validation
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