3P1C

Crystal structure of the bromodomain of human CREBBP in complex with acetylated lysine

3P1C の概要

• エントリーDOI: 10.2210/pdb3p1c/pdb
• 関連するPDBエントリー: 3P1D 3P1E 3P1F
• 分子名称: CREB-binding protein, N(6)-ACETYLLYSINE, THIOCYANATE ION, ... (5 entities in total)
• 機能のキーワード: structural genomics consortium, cbp, crebbp, creb binding protein isoform a, kat3a, rsts, rst, bromodomain, sgc, transcription
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cytoplasm: Q92793
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 28920.33

構造登録者

Filippakopoulos, P.,Picaud, S.,Feletar, I.,Fedorov, O.,Muniz, J.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Weigelt, J.,Bountra, C.,Knapp, S.,Structural Genomics Consortium (SGC) (登録日: 2010-09-30, 公開日: 2010-11-24, 最終更新日: 2023-12-06)

• 主引用文献: Filippakopoulos, P.,Picaud, S.,Mangos, M.,Keates, T.,Lambert, J.P.,Barsyte-Lovejoy, D.,Felletar, I.,Volkmer, R.,Muller, S.,Pawson, T.,Gingras, A.C.,Arrowsmith, C.H.,Knapp, S.; Histone recognition and large-scale structural analysis of the human bromodomain family.; Cell(Cambridge,Mass.), 149:214-231, 2012; PubMed: 22464331; DOI: 10.1016/j.cell.2012.02.013

実験手法

X-RAY DIFFRACTION (1.82 Å)