3P0H

Leishmania major Tyrosyl-tRNA synthetase in complex with fisetin, cubic crystal form

3P0H の概要

• エントリーDOI: 10.2210/pdb3p0h/pdb
• 関連するPDBエントリー: 3P0I 3P0J
• 分子名称: Tyrosyl-tRNA synthetase, 3,7,3',4'-TETRAHYDROXYFLAVONE (2 entities in total)
• 機能のキーワード: aminoacyl-trna synthetase, trna ligase, aars, tyrrs, pseudodimer, translation, atp-binding, nucleotide-binding, structural genomics, medical structural genomics of pathogenic protozoa, msgpp, ligase
• 由来する生物種: Leishmania major
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 154686.86

構造登録者

Larson, E.T.,Merritt, E.A.,Medical Structural Genomics of Pathogenic Protozoa (MSGPP) (登録日: 2010-09-28, 公開日: 2011-03-23, 最終更新日: 2023-12-06)

• 主引用文献: Larson, E.T.,Kim, J.E.,Castaneda, L.J.,Napuli, A.J.,Zhang, Z.,Fan, E.,Zucker, F.H.,Verlinde, C.L.,Buckner, F.S.,Van Voorhis, W.C.,Hol, W.G.,Merritt, E.A.; The Double-Length Tyrosyl-tRNA Synthetase from the Eukaryote Leishmania major Forms an Intrinsically Asymmetric Pseudo-Dimer.; J.Mol.Biol., 409:159-176, 2011; PubMed: 21420975; DOI: 10.1016/j.jmb.2011.03.026

実験手法

X-RAY DIFFRACTION (3 Å)