3OV6

CD1c in complex with MPM (mannosyl-beta1-phosphomycoketide)

3OV6 の概要

• エントリーDOI: 10.2210/pdb3ov6/pdb
• 分子名称: Beta-2-microglobulin, T-cell surface glycoprotein CD1c, T-cell surface glycoprotein CD1b, 2-acetamido-2-deoxy-beta-D-glucopyranose, DODECANE, ... (5 entities in total)
• 機能のキーワード: mhc, immunoglobulin domain, immune system, antigen presentation
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 45612.98

構造登録者

Scharf, L.,Li, N.S.,Hawk, A.J.,Garzon, D.,Zhang, T.,Kazen, A.R.,Shah, S.,Haddadian, E.J.,Saghatelian, A.,Faraldo-Gomez, J.D.,Meredith, S.C.,Piccirilli, J.A.,Adams, E.J. (登録日: 2010-09-15, 公開日: 2011-01-19, 最終更新日: 2020-07-29)

• 主引用文献: Scharf, L.,Li, N.S.,Hawk, A.J.,Garzon, D.,Zhang, T.,Fox, L.M.,Kazen, A.R.,Shah, S.,Haddadian, E.J.,Gumperz, J.E.,Saghatelian, A.,Faraldo-Gomez, J.D.,Meredith, S.C.,Piccirilli, J.A.,Adams, E.J.; The 2.5 A structure of CD1c in complex with a mycobacterial lipid reveals an open groove ideally suited for diverse antigen presentation; Immunity, 33:853-862, 2010; PubMed: 21167756; DOI: 10.1016/j.immuni.2010.11.026

実験手法

X-RAY DIFFRACTION (2.502 Å)