3OTS
MDR769 HIV-1 protease complexed with MA/CA hepta-peptide
Summary for 3OTS
Entry DOI | 10.2210/pdb3ots/pdb |
Related | 3OTY 3OU1 3OU3 3OU4 3OUA 3OUB 3OUC 3OUD |
Descriptor | Multi-drug resistant HIV-1 protease, MA/CA substrate peptide (3 entities in total) |
Functional Keywords | mdr hiv-1 protease, inhibitor, drug resistance, substrate envelope, hiv-1 protease, protease, substrate peptide, hydrolase, hydrolase-peptide complex, hydrolase/peptide |
Biological source | Human immunodeficiency virus 1 More |
Total number of polymer chains | 3 |
Total formula weight | 22340.17 |
Authors | Liu, Z.,Wang, Y.,Brunzelle, J.,Kovari, I.A.,Kovari, L.C. (deposition date: 2010-09-13, release date: 2011-03-30, Last modification date: 2024-02-21) |
Primary citation | Liu, Z.,Wang, Y.,Brunzelle, J.,Kovari, I.A.,Kovari, L.C. Nine Crystal Structures Determine the Substrate Envelope of the MDR HIV-1 Protease. Protein J., 30:173-183, 2011 Cited by PubMed: 21394574DOI: 10.1007/s10930-011-9316-2 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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