3OS1

PFV target capture complex (TCC) at 2.97 A resolution

3OS1 の概要

• エントリーDOI: 10.2210/pdb3os1/pdb
• 関連するPDBエントリー: 3L2R 3OS0 3OS2
• 分子名称: Integrase, DNA (5'-D(*AP*TP*TP*GP*TP*CP*AP*TP*GP*GP*AP*AP*TP*TP*TP*CP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*GP*AP*AP*AP*TP*TP*CP*CP*AP*TP*GP*AP*CP*(2DA))-3'), ... (7 entities in total)
• 機能のキーワード: protein-dna complex, tetramer, dna integration, endonuclease, metal-binding, multifunctional enzyme, nuclease, nucleotidyltransferase, nucleus, transferase, viral nucleoprotein, virion, dna-binding, zinc binding, hhcc motif, viral protein, recombination, recombination-dna complex, recombination/dna
• 由来する生物種: Human spumaretrovirus; 詳細
• 細胞内の位置: Integrase: Virion (Potential). Protease/Reverse transcriptase/ribonuclease H: Host nucleus (By similarity): P14350
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 109364.57

構造登録者

Maertens, G.N.,Hare, S.,Cherepanov, P. (登録日: 2010-09-08, 公開日: 2010-11-17, 最終更新日: 2023-11-01)

• 主引用文献: Maertens, G.N.,Hare, S.,Cherepanov, P.; The mechanism of retroviral integration from X-ray structures of its key intermediates; Nature, 468:326-329, 2010; PubMed: 21068843; DOI: 10.1038/nature09517

実験手法

X-RAY DIFFRACTION (2.97 Å)