3ORO

Mycobacterium tuberculosis PknB kinase domain L33D mutant (crystal form 4)

3ORO の概要

• エントリーDOI: 10.2210/pdb3oro/pdb
• 関連するPDBエントリー: 1mru 1o6y 3ori 3ork 3orl 3orm 3ORP 3ORT
• 分子名称: Serine/threonine protein kinase, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, ... (4 entities in total)
• 機能のキーワード: structural genomics, tb structural genomics consortium, tbsgc, kinase domain, signal transduction, transferase
• 由来する生物種: Mycobacterium tuberculosis
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 34251.14

構造登録者

Good, M.C.,Echols, N.,Lombana, T.N.,Alber, T.,TB Structural Genomics Consortium (TBSGC) (登録日: 2010-09-07, 公開日: 2010-12-15, 最終更新日: 2023-09-06)

• 主引用文献: Lombana, T.N.,Echols, N.,Good, M.C.,Thomsen, N.D.,Ng, H.L.,Greenstein, A.E.,Falick, A.M.,King, D.S.,Alber, T.; Allosteric activation mechanism of the Mycobacterium tuberculosis receptor Ser/Thr protein kinase, PknB.; Structure, 18:1667-1677, 2010; PubMed: 21134645; DOI: 10.1016/j.str.2010.09.019

実験手法

X-RAY DIFFRACTION (1.9 Å)