3OQA

Crystal Structures of Multidrug-Resistant Clinical Isolate 769 HIV-1 Protease Variants

Summary for 3OQA

• Entry DOI: 10.2210/pdb3oqa/pdb
• Related: 3OQ7 3OQD 3PJ6
• Descriptor: HIV-1 Protease (2 entities in total)
• Functional Keywords: protease, hydrolase
• Biological source: Human Immunodeficiency Virus 1 (HIV-1)
• Total number of polymer chains: 1
• Total formula weight: 10755.61

Authors

Yedidi, R.S.,Proteasa, G.,Martinez-Cajas, J.L.,Vickrey, J.F.,Martin, P.D.,Wawrzak, Z.,Kovari, L.C. (deposition date: 2010-09-02, release date: 2011-04-06, Last modification date: 2023-09-06)

• Primary citation: Yedidi, R.S.,Proteasa, G.,Martinez, J.L.,Vickrey, J.F.,Martin, P.D.,Wawrzak, Z.,Liu, Z.,Kovari, I.A.,Kovari, L.C.; Contribution of the 80s loop of HIV-1 protease to the multidrug-resistance mechanism: crystallographic study of MDR769 HIV-1 protease variants.; Acta Crystallogr.,Sect.D, 67:524-532, 2011; PubMed: 21636892; DOI: 10.1107/S0907444911011541

Experimental method

X-RAY DIFFRACTION (2.25 Å)