3OQ6
Horse liver alcohol dehydrogenase A317C mutant complexed with NAD+ and 2,3,4,5,6-pentafluorobenzyl alcohol
Summary for 3OQ6
Entry DOI | 10.2210/pdb3oq6/pdb |
Related | 1hld |
Descriptor | Alcohol dehydrogenase E chain, ZINC ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE (ACIDIC FORM), ... (6 entities in total) |
Functional Keywords | rossmann fold, alcohol metabolism, nad, oxidoreductase |
Biological source | Equus caballus (domestic horse,equine) |
Cellular location | Cytoplasm: P00327 |
Total number of polymer chains | 2 |
Total formula weight | 82109.86 |
Authors | Plapp, B.V.,Herdendorf, T.J. (deposition date: 2010-09-02, release date: 2010-11-10, Last modification date: 2023-09-06) |
Primary citation | Herdendorf, T.J.,Plapp, B.V. Origins of the high catalytic activity of human alcohol dehydrogenase 4 studied with horse liver A317C alcohol dehydrogenase. Chem.Biol.Interact, 191:42-47, 2011 Cited by PubMed: 21184752DOI: 10.1016/j.cbi.2010.12.015 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.2 Å) |
Structure validation
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