3OPT

Crystal structure of the Rph1 catalytic core with a-ketoglutarate

Summary for 3OPT

Entry DOI	10.2210/pdb3opt/pdb
Related	3OPW
Descriptor	DNA damage-responsive transcriptional repressor RPH1, 2-OXOGLUTARIC ACID, NICKEL (II) ION, ... (4 entities in total)
Functional Keywords	rph1, histone demethylase, catalytic core, oxidoreductase
Biological source	Saccharomyces cerevisiae (yeast)
Cellular location	Nucleus: P39956
Total number of polymer chains	1
Total formula weight	43818.40
Authors	Chang, Y.,Wu, J.,Tong, X.,Zhou, J.,Ding, J. (deposition date: 2010-09-02, release date: 2010-12-22, Last modification date: 2024-03-20)
Primary citation	Chang, Y.,Wu, J.,Tong, X.J.,Zhou, J.Q.,Ding, J. Crystal structure of the catalytic core of Saccharomyces cerevesiae histone demethylase Rph1: insights into the substrate specificity and catalytic mechanism Biochem.J., 433:295-302, 2011 Cited by PubMed: 21067515 DOI: 10.1042/BJ20101418 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation