3OPE

Structural Basis of Auto-inhibitory mechanism of Histone methyltransferase

3OPE の概要

• エントリーDOI: 10.2210/pdb3ope/pdb
• 分子名称: Probable histone-lysine N-methyltransferase ASH1L, ZINC ION, S-ADENOSYLMETHIONINE, ... (4 entities in total)
• 機能のキーワード: set, methyltransferase, nucleus, transferase
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 52561.55

構造登録者

An, S.,Song, J. (登録日: 2010-08-31, 公開日: 2011-01-12, 最終更新日: 2024-03-20)

• 主引用文献: An, S.,Yeo, K.J.,Jeon, Y.H.,Song, J.; Crystal structure of the human histone methyltransferase ASH1L catalytic domain and its implications for the regulatory mechanism; J.Biol.Chem., 286:8369-8374, 2011; PubMed: 21239497; DOI: 10.1074/jbc.M110.203380

実験手法

X-RAY DIFFRACTION (2.9 Å)