3OLT

X-ray crystal structure of arachidonic acid bound to the cyclooxygenase channel of R513H murine COX-2

3OLT の概要

• エントリーDOI: 10.2210/pdb3olt/pdb
• 関連するPDBエントリー: 1DIY 3HS5 3HS6 3HS7 3KRK 3MDL 3OLU
• 分子名称: Prostaglandin G/H synthase 2, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total)
• 機能のキーワード: monotopic membrane protein, oxidoreductase, n-glycosylation, membrane
• 由来する生物種: Mus musculus (mouse)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 141530.58

構造登録者

Vecchio, A.J.,Malkowski, M.G. (登録日: 2010-08-26, 公開日: 2011-04-13, 最終更新日: 2023-09-06)

• 主引用文献: Vecchio, A.J.,Malkowski, M.G.; The structural basis of endocannabinoid oxygenation by cyclooxygenase-2.; J.Biol.Chem., 286:20736-20745, 2011; PubMed: 21489986; DOI: 10.1074/jbc.M111.230367

実験手法

X-RAY DIFFRACTION (2.45 Å)