3OII

Crystal structure of Saccharomyces Cerevisiae Nep1/Emg1 bound to S-adenosylhomocysteine

Summary for 3OII

Entry DOI	10.2210/pdb3oii/pdb
Related	3O7B 3OIJ 3OIN
Descriptor	Essential for mitotic growth 1, S-ADENOSYL-L-HOMOCYSTEINE, GLYCEROL, ... (4 entities in total)
Functional Keywords	emg1, scnep1, spout, ribosome biogenesis, methyltransferase, rrna processing, ribosomal protein
Biological source	Saccharomyces cerevisiae (yeast)
Cellular location	Nucleus, nucleolus : Q06287
Total number of polymer chains	2
Total formula weight	56847.94
Authors	Thomas, S.R.,Szyk, A.,LaRonde-LeBlanc, N. (deposition date: 2010-08-19, release date: 2010-12-01, Last modification date: 2023-09-06)
Primary citation	Thomas, S.R.,Keller, C.A.,Szyk, A.,Cannon, J.R.,Laronde-Leblanc, N.A. Structural insight into the functional mechanism of Nep1/Emg1 N1-specific pseudouridine methyltransferase in ribosome biogenesis. Nucleic Acids Res., 39:2445-2457, 2011 Cited by PubMed: 21087996 DOI: 10.1093/nar/gkq1131 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.85 Å)

Structure validation