3OHT

Crystal Structure of Salmo Salar p38alpha

3OHT の概要

• エントリーDOI: 10.2210/pdb3oht/pdb
• 分子名称: p38a, N-(2-CHLORO-6-METHYLPHENYL)-2-({6-[4-(2-HYDROXYETHYL)PIPERAZIN-1-YL]-2-METHYLPYRIMIDIN-4-YL}AMINO)-1,3-THIAZOLE-5-CARBOXAMIDE, SULFATE ION, ... (4 entities in total)
• 機能のキーワード: kinase serine/threonine-protein kinase transferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• 由来する生物種: Salmo salar (Atlantic salmon)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 92060.12

構造登録者

Rothweiler, U.,Johnson, K.,Engh, R.A. (登録日: 2010-08-18, 公開日: 2011-06-29, 最終更新日: 2023-09-06)

• 主引用文献: Rothweiler, U.,Aberg, E.,Johnson, K.A.,Hansen, T.E.,Jorgensen, J.B.,Engh, R.A.; p38alpha MAP kinase dimers with swapped activation segments and a novel catalytic loop conformation; J.Mol.Biol., 411:474-485, 2011; PubMed: 21699901; DOI: 10.1016/j.jmb.2011.06.013

実験手法

X-RAY DIFFRACTION (2.7 Å)