3OH3

Protein structure of USP from L. major bound to URIDINE-5'-DIPHOSPHATE -Arabinose

3OH3 の概要

• エントリーDOI: 10.2210/pdb3oh3/pdb
• 関連するPDBエントリー: 3OGZ 3OH0 3OH1 3OH2 3OH4
• 分子名称: UDP-sugar pyrophosphorylase, [(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl (2S,3R,4S,5S)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl dihydrogen diphosphate, GLYCEROL, ... (4 entities in total)
• 機能のキーワード: left handed beta helix, rossmann fold, udp sugar pyrophosphorylase, transferase
• 由来する生物種: Leishmania major
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 71260.40

構造登録者

Dickmanns, A.,Damerow, S.,Neumann, P.,Schulz, E.-C.,Lamerz, A.,Routier, F.,Ficner, R. (登録日: 2010-08-17, 公開日: 2010-11-17, 最終更新日: 2023-09-06)

• 主引用文献: Dickmanns, A.,Damerow, S.,Neumann, P.,Schulz, E.C.,Lamerz, A.C.,Routier, F.H.,Ficner, R.; Structural basis for the broad substrate range of the UDP-sugar pyrophosphorylase from Leishmania major.; J.Mol.Biol., 405:461-478, 2011; PubMed: 21073876; DOI: 10.1016/j.jmb.2010.10.057

実験手法

X-RAY DIFFRACTION (2.03 Å)