3OAU

Antibody 2G12 Recognizes Di-Mannose Equivalently in Domain- and Non-Domain-Exchanged Forms, but only binds the HIV-1 Glycan Shield if Domain-Exchanged

Summary for 3OAU

• Entry DOI: 10.2210/pdb3oau/pdb
• Related: 3OAY 3OAZ 3OB0
• Related PRD ID: PRD_900111
• Descriptor: Fab 2G12, heavy chain, Fab 2G12, light chain, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose, ... (6 entities in total)
• Functional Keywords: fab, immune system
• Biological source: Homo sapiens; More
• Total number of polymer chains: 2
• Total formula weight: 47734.18

Authors

Doores, K.J.,Fulton, Z.,Huber, M.,Wilson, I.A.,Burton, D.R. (deposition date: 2010-08-05, release date: 2011-01-12, Last modification date: 2020-07-29)

• Primary citation: Doores, K.J.,Fulton, Z.,Huber, M.,Wilson, I.A.,Burton, D.R.; Antibody 2G12 recognizes di-mannose equivalently in domain- and nondomain-exchanged forms but only binds the HIV-1 glycan shield if domain exchanged.; J.Virol., 84:10690-10699, 2010; PubMed: 20702629; DOI: 10.1128/JVI.01110-10

Experimental method

X-RAY DIFFRACTION (1.9 Å)