3O76
1.8 Angstroms molecular structure of mouse liver glutathione S-transferase mutant C47A complexed with S-(P-nitrobenzyl)glutathione
Summary for 3O76
Entry DOI | 10.2210/pdb3o76/pdb |
Related | 1GLQ |
Descriptor | Glutathione S-transferase P 1, S-(P-NITROBENZYL)GLUTATHIONE (3 entities in total) |
Functional Keywords | transferase(glutathione), transferase |
Biological source | Mus musculus (mouse) |
Total number of polymer chains | 2 |
Total formula weight | 47828.68 |
Authors | Canals, A.,Coll, M. (deposition date: 2010-07-30, release date: 2011-06-15, Last modification date: 2023-09-06) |
Primary citation | McManus, G.,Costa, M.,Canals, A.,Coll, M.,Mantle, T.J. Site-directed mutagenesis of mouse glutathione transferase P1-1 unlocks masked cooperativity, introduces a novel mechanism for 'ping pong' kinetic behaviour, and provides further structural evidence for participation of a water molecule in proton abstraction from glutathione. Febs J., 278:273-281, 2011 Cited by PubMed: 21134126DOI: 10.1111/j.1742-4658.2010.07944.x PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.77 Å) |
Structure validation
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