3O3H
T. maritima RNase H2 D107N in complex with nucleic acid substrate and manganese ions
Summary for 3O3H
Entry DOI | 10.2210/pdb3o3h/pdb |
Related | 2etj 3O3F 3O3G |
Descriptor | Ribonuclease HII, DNA (5'-D(*GP*AP*AP*TP*CP*AP*GP*GP*TP*GP*TP*C)-3'), DNA/RNA (5'-D(*GP*AP*CP*AP*C)-R(P*C)-D(P*TP*GP*AP*TP*TP*C)-3'), ... (5 entities in total) |
Functional Keywords | rnase h fold, nuclease, hydrolase-dna-rna hybrid complex, hydrolase/dna-rna hybrid |
Biological source | Thermotoga maritima |
Cellular location | Cytoplasm (Potential): Q9X017 |
Total number of polymer chains | 3 |
Total formula weight | 32188.27 |
Authors | Rychlik, M.P.,Chon, H.,Cerritelli, S.M.,Klimek, P.,Crouch, R.J.,Nowotny, M. (deposition date: 2010-07-24, release date: 2010-12-08, Last modification date: 2024-02-21) |
Primary citation | Rychlik, M.P.,Chon, H.,Cerritelli, S.M.,Klimek, P.,Crouch, R.J.,Nowotny, M. Crystal Structures of RNase H2 in Complex with Nucleic Acid Reveal the Mechanism of RNA-DNA Junction Recognition and Cleavage. Mol.Cell, 40:658-670, 2010 Cited by PubMed: 21095591DOI: 10.1016/j.molcel.2010.11.001 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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