3NXQ

Angiotensin Converting Enzyme N domain glycsoylation mutant (Ndom389) in complex with RXP407

3NXQ の概要

• エントリーDOI: 10.2210/pdb3nxq/pdb
• 関連するBIRD辞書のPRD_ID: PRD_001050
• 分子名称: Angiotensin-converting enzyme, TETRAETHYLENE GLYCOL, alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (11 entities in total)
• 機能のキーワード: dicarboxy zinc metallopeptidase, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 150625.89

構造登録者

Anthony, C.S.,Corradi, H.R.,Schwager, S.L.U.,Redelinghuys, P.,Georgiadis, D.,Dive, V.,Acharya, K.R.,Sturrock, E.D. (登録日: 2010-07-14, 公開日: 2010-09-08, 最終更新日: 2020-07-29)

• 主引用文献: Anthony, C.S.,Corradi, H.R.,Schwager, S.L.,Redelinghuys, P.,Georgiadis, D.,Dive, V.,Acharya, K.R.,Sturrock, E.D.; The N domain of human angiotensin-I-converting enzyme: the role of N-glycosylation and the crystal structure in complex with an N domain-specific phosphinic inhibitor, RXP407.; J.Biol.Chem., 285:35685-35693, 2010; PubMed: 20826823; DOI: 10.1074/jbc.M110.167866

実験手法

X-RAY DIFFRACTION (1.99 Å)