3NXD

JC polyomavirus VP1 in complex with LSTc

Summary for 3NXD

Entry DOI	10.2210/pdb3nxd/pdb
Related	1vps 3NXG 3bwr
Descriptor	Major capsid protein VP1, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, GLYCEROL, ... (5 entities in total)
Functional Keywords	beta-sandwich with jelly roll topology, major capsid protein, viral protein
Biological source	JC polyomavirus (JCPyV)
Cellular location	Virion: P03089
Total number of polymer chains	5
Total formula weight	153209.95
Authors	Neu, U.,Stroeh, L.J.,Stehle, T. (deposition date: 2010-07-13, release date: 2010-11-17, Last modification date: 2024-02-21)
Primary citation	Neu, U.,Maginnis, M.S.,Palma, A.S.,Stroh, L.J.,Nelson, C.D.,Feizi, T.,Atwood, W.J.,Stehle, T. Structure-function analysis of the human JC polyomavirus establishes the LSTc pentasaccharide as a functional receptor motif. Cell Host Microbe, 8:309-319, 2010 Cited by PubMed: 20951965 DOI: 10.1016/j.chom.2010.09.004 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation