3NV0

Crystal structure and mutational analysis of the NXF2/NXT1 heterodimeric complex from caenorhabditis elegans at 1.84 A resolution

3NV0 の概要

• エントリーDOI: 10.2210/pdb3nv0/pdb
• 分子名称: Nuclear RNA export factor 2, NTF2-related export protein, DI(HYDROXYETHYL)ETHER, ... (7 entities in total)
• 機能のキーワード: ntf2-like domain, beta sheet heterodimer interface, nucleoporin binding pocket, water mediated interface, cation-pi interactions, pi-pi interactions, nxf-loop, ntf2-plug, intramonomer buried waters, novel surface exposed pockets, mrna transport, nucleus, rna-binding, rna binding-protein transport complex, rna binding/protein transport
• 由来する生物種: Caenorhabditis elegans (nematode); 詳細
• 細胞内の位置: Nucleus: Q9XVS8; Nucleus (By similarity): Q9U757
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 41997.40

構造登録者

Kerkow, D.E.,Carmel, A.B.,Williamson, J.R. (登録日: 2010-07-07, 公開日: 2011-07-20, 最終更新日: 2024-02-21)

• 主引用文献: Kerkow, D.E.,Carmel, A.B.,Menichelli, E.,Ambrus, G.,Hills, R.D.,Gerace, L.,Williamson, J.R.; The structure of the NXF2/NXT1 heterodimeric complex reveals the combined specificity and versatility of the NTF2-like fold.; J.Mol.Biol., 415:649-665, 2012; PubMed: 22123199; DOI: 10.1016/j.jmb.2011.11.027

実験手法

X-RAY DIFFRACTION (1.84 Å)