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3NUY

phosphoinositide-dependent kinase-1 (PDK1) with fragment17

Summary for 3NUY
Entry DOI10.2210/pdb3nuy/pdb
Related3NUN 3NUS 3NUU
DescriptorPkB-like, GLYCEROL, SULFATE ION, ... (5 entities in total)
Functional Keywordskinase domain, transferase
Biological sourceHomo sapiens (human)
Total number of polymer chains1
Total formula weight33910.46
Authors
Campobasso, N.,Ward, P. (deposition date: 2010-07-07, release date: 2011-05-25, Last modification date: 2018-10-10)
Primary citationMedina, J.R.,Blackledge, C.W.,Heerding, D.A.,Campobasso, N.,Ward, P.,Briand, J.,Wright, L.,Axten, J.M.
Aminoindazole PDK1 Inhibitors: A Case Study in Fragment-Based Drug Discovery.
ACS Med Chem Lett, 1:439-442, 2010
Cited by
PubMed: 24900229
DOI: 10.1021/ml100136n
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.1 Å)
Structure validation

217705

數據於2024-03-27公開中

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