3NUS

phosphoinositide-dependent kinase-1 (PDK1) with fragment8

Summary for 3NUS

• Entry DOI: 10.2210/pdb3nus/pdb
• Related: 3NUN 3NUU 3NUY
• Descriptor: phosphoinositide-dependent kinase-1, GLYCEROL, 1H-indazol-3-amine, ... (5 entities in total)
• Functional Keywords: kinase domain, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 33897.47

Authors

Campobasso, N.,Ward, P. (deposition date: 2010-07-07, release date: 2011-05-25, Last modification date: 2018-10-10)

• Primary citation: Medina, J.R.,Blackledge, C.W.,Heerding, D.A.,Campobasso, N.,Ward, P.,Briand, J.,Wright, L.,Axten, J.M.; Aminoindazole PDK1 Inhibitors: A Case Study in Fragment-Based Drug Discovery.; ACS Med Chem Lett, 1:439-442, 2010; PubMed: 24900229; DOI: 10.1021/ml100136n

Experimental method

X-RAY DIFFRACTION (2.75 Å)