3NUG

Crystal structure of wild type tetrameric pyridoxal 4-dehydrogenase from Mesorhizobium loti

Summary for 3NUG

Entry DOI	10.2210/pdb3nug/pdb
Descriptor	3-oxoacyl-(Acyl-carrier protein) reductase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ACETIC ACID, ... (4 entities in total)
Functional Keywords	pyridoxal, tpldh, 4-pyridoxolactone, short chain dehydrogenase/reductase, oxidoreductase
Biological source	Mesorhizobium loti
Total number of polymer chains	4
Total formula weight	104421.41
Authors	Chu, H.N. (deposition date: 2010-07-06, release date: 2011-04-20, Last modification date: 2023-11-01)
Primary citation	Chu, H.N.,Kobayashi, J.,Mikami, B.,Yagi, T. The crystal structure of SDR-type pyridoxal 4-dehydrogenase of Mesorhizobium loti Biosci.Biotechnol.Biochem., 75:388-390, 2011 Cited by PubMed Abstract: Pyridoxal 4-dehydrogenase catalyzes the irreversible oxidation of pyridoxal to 4-pyridoxolactone and is involved in degradation pathway I of pyridoxine, a vitamin B(6) compound. Its crystal structure was elucidated for the first time. Molecular replacement with (S)-1-phenylthanol dehydrogenase (PDB code 2EW8) was adopted to determine the tertiary structure of the NAD(+)-bound enzyme. PubMed: 21307574 DOI: 10.1271/bbb.100748 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.788 Å)

Structure validation