3NUE

The structure of 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase from mycobacterium tuberculosis complexed with tryptophan

Summary for 3NUE

Entry DOI	10.2210/pdb3nue/pdb
Related	2B7O 3KGF 3NUD 3NV8
Descriptor	Probable 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase AroG, MANGANESE (II) ION, TRYPTOPHAN, ... (9 entities in total)
Functional Keywords	mycobacterium tuberculosis, dah7p synthase, shikimate pathway, aromatic biosynthesis, evolutionary relationships, transferase, trp-bound, augmented tim-barrel structure
Biological source	Mycobacterium tuberculosis
Total number of polymer chains	2
Total formula weight	103968.18
Authors	Parker, E.J.,Jameson, G.B.,Jiao, W.,Webby, C.J.,Baker, E.N.,Baker, H.M. (deposition date: 2010-07-06, release date: 2010-07-28, Last modification date: 2023-11-01)
Primary citation	Webby, C.J.,Jiao, W.,Hutton, R.D.,Blackmore, N.J.,Baker, H.M.,Baker, E.N.,Jameson, G.B.,Parker, E.J. Synergistic allostery, a sophisticated regulatory network for the control of aromatic amino acid biosynthesis in Mycobacterium tuberculosis J.Biol.Chem., 285:30567-30576, 2010 Cited by PubMed: 20667835 DOI: 10.1074/jbc.M110.111856 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation