3NS5

Crystal structure of the RNA recognition motif of yeast eIF3b residues 76-161

3NS5 の概要

• エントリーDOI: 10.2210/pdb3ns5/pdb
• 関連するPDBエントリー: 3NS6
• 分子名称: Eukaryotic translation initiation factor 3 subunit B (2 entities in total)
• 機能のキーワード: translation
• 由来する生物種: Saccharomyces cerevisiae (yeast)
• 細胞内の位置: Cytoplasm (Probable): P06103
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 19969.75

構造登録者

Khoshnevis, S.,Neumann, P.,Ficner, R. (登録日: 2010-07-01, 公開日: 2010-10-06, 最終更新日: 2023-09-06)

主引用文献

Khoshnevis, S.,Neumann, P.,Ficner, R.
Crystal structure of the RNA recognition motif of yeast translation initiation factor eIF3b reveals differences to human eIF3b.
Plos One, 5:e12784-e12784, 2010

PubMed Abstract: The multi-subunit eukaryotic initiation factor3 (eIF3) plays a central role in the initiation step of protein synthesis in eukaryotes. One of its large subunits, eIF3b, serves as a scaffold within eIF3 as it interacts with several other subunits. It harbors an RNA Recognition Motif (RRM), which is shown to be a non-canonical RRM in human as it is not capable to interact with oligonucleotides, but rather interacts with eIF3j, a sub-stoichiometric subunit of eIF3.

PubMed: 20862284
DOI: 10.1371/journal.pone.0012784

実験手法

X-RAY DIFFRACTION (2.598 Å)