3NR9

Structure of human CDC2-like kinase 2 (CLK2)

3NR9 の概要

• エントリーDOI: 10.2210/pdb3nr9/pdb
• 分子名称: Dual specificity protein kinase CLK2, (5Z)-5-(quinolin-6-ylmethylidene)-2-[(thiophen-2-ylmethyl)amino]-1,3-thiazol-4(5H)-one (3 entities in total)
• 機能のキーワード: structural genomics consortium, sgc, protein kinase, dual specificity protein kinase, transferase
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Isoform 1: Nucleus. Isoform 2: Nucleus speckle: P49760
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 131218.88

構造登録者

Chaikuad, A.,Savitsky, P.,Krojer, T.,Muniz, J.R.C.,Filippakopoulos, P.,Rellos, P.,Keates, T.,Fedorov, O.,Pike, A.C.W.,Eswaran, J.,Berridge, G.,Phillips, C.,Zhang, Y.,von Delft, F.,Weigelt, J.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Knapp, S.,Structural Genomics Consortium (SGC) (登録日: 2010-06-30, 公開日: 2010-08-25, 最終更新日: 2023-09-06)

• 主引用文献: Chaikuad, A.,Savitsky, P.,Krojer, T.,Muniz, J.R.C.,Filippakopoulos, P.,Rellos, P.,Keates, T.,Fedorov, O.,Pike, A.C.W.,Eswaran, J.,Berridge, G.,Phillips, C.,Zhang, Y.,von Delft, F.,Weigelt, J.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Knapp, S.,Structural Genomics Consortium (SGC); Structure of human CDC2-like kinase 2 (CLK2); To be Published,

実験手法

X-RAY DIFFRACTION (2.89 Å)