3NQ8

Optimization of the in silico designed Kemp eliminase KE70 by computational design and directed evolution R4 8/5A

Summary for 3NQ8

Entry DOI	10.2210/pdb3nq8/pdb
Related	3NPU 3NPV 3NPW 3NPX 3NQ2 3NQV 3NR0
Descriptor	deoxyribose phosphate aldolase, NITRATE ION, BENZAMIDINE, ... (4 entities in total)
Functional Keywords	tim, structural genomics, israel structural proteomics center, ispc, lyase
Biological source	Escherichia coli
Total number of polymer chains	1
Total formula weight	28741.52
Authors	Khersonsky, O.,Rothlisberge, D.,Wollacott, A.M.,Dym, O.,Baker, D.,Tawfik, D.S.,Israel Structural Proteomics Center (ISPC) (deposition date: 2010-06-29, release date: 2011-02-09, Last modification date: 2023-11-01)
Primary citation	Khersonsky, O.,Rothlisberger, D.,Wollacott, A.M.,Murphy, P.,Dym, O.,Albeck, S.,Kiss, G.,Houk, K.N.,Baker, D.,Tawfik, D.S. Optimization of the in-silico-designed kemp eliminase KE70 by computational design and directed evolution J.Mol.Biol., 407:391-412, 2011 Cited by PubMed: 21277311 DOI: 10.1016/j.jmb.2011.01.041 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.4 Å)

Structure validation