3NOA

Crystal structure of human PPAR-gamma ligand binding domain complex with a potency improved agonist

3NOA の概要

• エントリーDOI: 10.2210/pdb3noa/pdb
• 分子名称: Peroxisome proliferator-activated receptor gamma, (5-{3-[4-(biphenyl-4-ylcarbonyl)-2-propylphenoxy]propoxy}-1H-indol-1-yl)acetic acid (3 entities in total)
• 機能のキーワード: hypoglycemic agents, models, molecular, ppar alpha, ppar gamma, protein isoforms, quinolines, structure-activity relationship, thiazolidinediones, transcription
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Nucleus: P37231
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 63089.32

構造登録者

Peng, Y.H.,Wu, J.S.,Wu, S.Y. (登録日: 2010-06-25, 公開日: 2011-06-29, 最終更新日: 2023-11-01)

• 主引用文献: Peng, Y.H.,Coumar, M.S.,Leou, J.S.,Wu, J.S.,Shiao, H.Y.,Lin, C.H.,Lyu, P.C.,Hsieh, H.P.,Wu, S.Y.; Crystal structure of human PPAR-gamma ligand binding domain complex with a potency improved agonist; To be published,

実験手法

X-RAY DIFFRACTION (1.98 Å)