3NIG

The Closed Headpiece of Integrin IIb 3 and its Complex with an IIb 3 -Specific Antagonist That Does Not Induce Opening

3NIG の概要

• エントリーDOI: 10.2210/pdb3nig/pdb
• 関連するPDBエントリー: 2VDR 3NID 3NIF
• 分子名称: Integrin alpha-IIb, MAGNESIUM ION, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (12 entities in total)
• 機能のキーワード: integrin, headpiece, alphaiib, beta3, cell adhesion-immune system complex, cell adhesion-blood clotting complex, cell adhesion/blood clotting
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 300994.33

構造登録者

Zhu, J.H.,Zhu, J.Q.,Springer, T.A. (登録日: 2010-06-15, 公開日: 2010-12-22, 最終更新日: 2023-09-06)

• 主引用文献: Zhu, J.,Zhu, J.,Negri, A.,Provasi, D.,Filizola, M.,Coller, B.S.,Springer, T.A.; Closed headpiece of integrin {alpha}IIb{beta}3 and its complex with an {alpha}IIb{beta}3-specific antagonist that does not induce opening.; Blood, 116:5050-5059, 2010; PubMed: 20679525; DOI: 10.1182/blood-2010-04-281154

実験手法

X-RAY DIFFRACTION (2.25 Å)