Crystal structure of the human CNOT6L nuclease domain in complex with AMP

Summary for 3NGN

Related3NGO 3NGQ
DescriptorCCR4-NOT transcription complex subunit 6-like, ADENOSINE MONOPHOSPHATE (3 entities in total)
Functional Keywordsprotein-amp complex, hydrolase
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm Q96LI5
Total number of polymer chains1
Total molecular weight45834.94
Wang, H.,Morita, M.,Yang, W.,Bartlam, M.,Yamamoto, T.,Rao, Z. (deposition date: 2010-06-12, release date: 2010-07-28, Last modification date: 2011-07-13)
Primary citation
Wang, H.,Morita, M.,Yang, X.,Suzuki, T.,Yang, W.,Wang, J.,Ito, K.,Wang, Q.,Zhao, C.,Bartlam, M.,Yamamoto, T.,Rao, Z.
Crystal structure of the human CNOT6L nuclease domain reveals strict poly(A) substrate specificity.
Embo J., 2010
PubMed: 20628353 (PDB entries with the same primary citation)
DOI: 10.1038/emboj.2010.152
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.25371.0%7.5%2.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution