3NGA
Human CK2 catalytic domain in complex with CX-4945
Summary for 3NGA
Entry DOI | 10.2210/pdb3nga/pdb |
Descriptor | Casein kinase II subunit alpha, 5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid, SULFATE ION, ... (4 entities in total) |
Functional Keywords | kinase, ck2, inhibitor, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 81128.97 |
Authors | Ferguson, A.D. (deposition date: 2010-06-11, release date: 2010-12-15, Last modification date: 2024-02-21) |
Primary citation | Ferguson, A.D.,Sheth, P.R.,Basso, A.D.,Paliwal, S.,Gray, K.,Fischmann, T.O.,Le, H.V. Structural basis of CX-4945 binding to human protein kinase CK2. Febs Lett., 585:104-110, 2011 Cited by PubMed: 21093442DOI: 10.1016/j.febslet.2010.11.019 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.71 Å) |
Structure validation
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