3NFB

Crystal structure of the N-terminal beta-aminopeptidase BapA in complex with hydrolyzed ampicillin

3NFB の概要

• エントリーDOI: 10.2210/pdb3nfb/pdb
• 関連するPDBエントリー: 1B65 3N2W 3N33 3NDV
• 分子名称: Beta-peptidyl aminopeptidase, GLYCEROL, (2S,4S)-2-[(R)-{[(2R)-2-amino-2-phenylacetyl]amino}(carboxy)methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, ... (5 entities in total)
• 機能のキーワード: ntn-hydrolase, alpha-beta-beta-alpha sandwich, beta-peptide cleaving enzyme, hydrolase-inhibitor complex, hydrolase/inhibitor
• 由来する生物種: Sphingosinicella xenopeptidilytica
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 157496.49

構造登録者

Merz, T.,Heck, T.,Geueke, B.,Kohler, H.-P.E.,Gruetter, M.G. (登録日: 2010-06-10, 公開日: 2011-09-28, 最終更新日: 2023-09-06)

• 主引用文献: Heck, T.,Merz, T.,Geueke, B.,Gruetter, M.G.,Kohler, H.-P.E.; Crystal structure and inhibition of the beta-aminopeptidase BapA, a new ampicillin-recognizing member of the N-terminal nucleophile hydrolase family; To be Published,

実験手法

X-RAY DIFFRACTION (1.85 Å)