3NDE

Crystal Structure of BlaC-E166A covalently bound with Cephalotin

Summary for 3NDE

• Entry DOI: 10.2210/pdb3nde/pdb
• Descriptor: Beta-lactamase, PHOSPHATE ION, (2R)-5-[(acetyloxy)methyl]-2-{(1R)-2-oxo-1-[(thiophen-2-ylacetyl)amino]ethyl}-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid, ... (4 entities in total)
• Functional Keywords: penicillin binding protein, beta-lactam covalent adduct, hydrolase-antibiotic complex, hydrolase/antibiotic
• Biological source: Mycobacterium tuberculosis
• Total number of polymer chains: 1
• Total formula weight: 28803.08

Authors

Tremblay, L.W.,Blanchard, J.S. (deposition date: 2010-06-07, release date: 2011-12-14, Last modification date: 2017-11-08)

• Primary citation: Tremblay, L.W.,Blanchard, J.S.; BlaC-E166A covalently bound with cephalosporins and penicillins; To be Published,

Experimental method

X-RAY DIFFRACTION (1.7 Å)