3N9G

Crystal structure of the Fab fragment of the human neutralizing anti-West Nile Virus MAb CR4354

Summary for 3N9G

• Entry DOI: 10.2210/pdb3n9g/pdb
• EMDB information: 5190
• Descriptor: Fab fragment of MAb CR4354, heavy chain, Fab fragment of MAb CR4354, light chain (3 entities in total)
• Functional Keywords: fab fragment, human neutralizing antibody, mab cr4354, immune system, anti-west nile virus
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 47653.86

Authors

Kaufmann, B.,Rossmann, M.G. (deposition date: 2010-05-29, release date: 2010-11-24, Last modification date: 2023-09-06)

• Primary citation: Kaufmann, B.,Vogt, M.R.,Goudsmit, J.,Holdaway, H.A.,Aksyuk, A.A.,Chipman, P.R.,Kuhn, R.J.,Diamond, M.S.,Rossmann, M.G.; Neutralization of West Nile virus by cross-linking of its surface proteins with Fab fragments of the human monoclonal antibody CR4354.; Proc.Natl.Acad.Sci.USA, 107:18950-18955, 2010; PubMed: 20956322; DOI: 10.1073/pnas.1011036107

Experimental method

X-RAY DIFFRACTION (1.434 Å)