3N6N
crystal structure of EV71 RdRp in complex with Br-UTP
Summary for 3N6N
Entry DOI | 10.2210/pdb3n6n/pdb |
Related | 3N6L 3N6M |
Descriptor | RNA-dependent RNA polymerase, NICKEL (II) ION, 5-bromouridine 5'-(tetrahydrogen triphosphate), ... (4 entities in total) |
Functional Keywords | ev71, rdrp, br-utp, transferase |
Biological source | Human enterovirus 71 |
Total number of polymer chains | 1 |
Total formula weight | 53167.35 |
Authors | |
Primary citation | Wu, Y.,Lou, Z.,Miao, Y.,Yu, Y.,Dong, H.,Peng, W.,Bartlam, M.,Li, X.,Rao, Z. Structures of EV71 RNA-dependent RNA polymerase in complex with substrate and analogue provide a drug target against the hand-foot-and-mouth disease pandemic in China. Protein Cell, 1:491-500, 2010 Cited by PubMed: 21203964DOI: 10.1007/s13238-010-0061-7 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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