3N6M

Crystal structure of EV71 RdRp in complex with GTP

Summary for 3N6M

• Entry DOI: 10.2210/pdb3n6m/pdb
• Related: 3N6L 3N6N
• Descriptor: RNA-dependent RNA polymerase, NICKEL (II) ION, GUANOSINE-5'-TRIPHOSPHATE, ... (4 entities in total)
• Functional Keywords: ev71, rdrp, gtp, transferase
• Biological source: Human enterovirus 71
• Total number of polymer chains: 1
• Total formula weight: 53127.49

Authors

Wu, Y.,Lou, Z.Y.,Miao, Y.,Yu, Y.,Rao, Z.H. (deposition date: 2010-05-26, release date: 2011-06-15, Last modification date: 2024-03-20)

• Primary citation: Wu, Y.,Lou, Z.,Miao, Y.,Yu, Y.,Dong, H.,Peng, W.,Bartlam, M.,Li, X.,Rao, Z.; Structures of EV71 RNA-dependent RNA polymerase in complex with substrate and analogue provide a drug target against the hand-foot-and-mouth disease pandemic in China.; Protein Cell, 1:491-500, 2010; PubMed: 21203964; DOI: 10.1007/s13238-010-0061-7

Experimental method

X-RAY DIFFRACTION (2.5 Å)