3N2Z

The Structure of Human Prolylcarboxypeptidase at 2.80 Angstroms Resolution

3N2Z の概要

• エントリーDOI: 10.2210/pdb3n2z/pdb
• 関連するPDBエントリー: 3JYH
• 分子名称: Lysosomal Pro-X carboxypeptidase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• 機能のキーワード: alpha/beta hydrolase, prcp, serine carboxypeptidase, hydrolase
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Lysosome: P42785
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 51976.46

構造登録者

Soisson, S.M.,Patel, S.B.,Lumb, K.J.,Sharma, S. (登録日: 2010-05-19, 公開日: 2010-07-07, 最終更新日: 2024-10-16)

主引用文献

Soisson, S.M.,Patel, S.B.,Abeywickrema, P.D.,Bryne, N.J.,Diehl, R.E.,Hall, D.L.,Ford, R.E.,Reid, J.C.,Rickert, K.W.,Shipman, J.M.,Sharma, S.,Lumb, K.J.
Structural definition and substrate specificity of the S28 protease family: the crystal structure of human prolylcarboxypeptidase.
Bmc Struct.Biol., 10:16-16, 2010

PubMed Abstract: The unique S28 family of proteases is comprised of the carboxypeptidase PRCP and the aminopeptidase DPP7. The structural basis of the different substrate specificities of the two enzymes is not understood nor has the structure of the S28 fold been described.

PubMed: 20540760
DOI: 10.1186/1472-6807-10-16

実験手法

X-RAY DIFFRACTION (2.79 Å)