3N2E

Crystal structure of Helicobactor pylori shikimate kinase in complex with NSC162535

Summary for 3N2E

Entry DOI	10.2210/pdb3n2e/pdb
Related	1ZUH 1ZUI 3HR7 3MRS 3MUF
Descriptor	Shikimate kinase, 7-amino-4-hydroxy-3-[(E)-(5-hydroxy-7-sulfonaphthalen-2-yl)diazenyl]naphthalene-2-sulfonic acid, L(+)-TARTARIC ACID, ... (4 entities in total)
Functional Keywords	alpha-beta-alpha fold, transferase
Biological source	Helicobacter pylori
Cellular location	Cytoplasm (Probable): P56073
Total number of polymer chains	3
Total formula weight	58741.80
Authors	Cheng, W.C.,Chen, T.J.,Lin, S.C.,Wang, W.C. (deposition date: 2010-05-18, release date: 2011-05-18, Last modification date: 2023-11-01)
Primary citation	Cheng, W.C.,Chen, Y.F.,Wang, H.J.,Hsu, K.C.,Lin, S.C.,Chen, T.J.,Yang, J.M.,Wang, W.C. Structures of Helicobacter pylori shikimate kinase reveal a selective inhibitor-induced-fit mechanism Plos One, 7:e33481-e33481, 2012 Cited by PubMed: 22438938 DOI: 10.1371/journal.pone.0033481 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.53 Å)

Structure validation