3N0D
Crystal structure of WDR5 mutant (W330F)
Summary for 3N0D
Entry DOI | 10.2210/pdb3n0d/pdb |
Related | 3MXX 3N0E |
Descriptor | WD repeat-containing protein 5 (2 entities in total) |
Functional Keywords | wdr5, wd-repeat protein 5, asp-his-ser-trp tetrad, thermostability, circular dichroism, folding energy, guanidine hydrochloride, transcription |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus: P61964 |
Total number of polymer chains | 1 |
Total formula weight | 34589.19 |
Authors | Wu, Y.-D.,Wu, X.-H.,Gao, Y.,Chen, R.-C. (deposition date: 2010-05-13, release date: 2010-10-20, Last modification date: 2023-11-01) |
Primary citation | Wu, X.-H.,Chen, R.-C.,Gao, Y.,Wu, Y.-D. The Effect of Asp-His-Ser/Thr-Trp Tetrad on the Thermostability of WD40-Repeat Proteins Biochemistry, 49:10237-10245, 2010 Cited by PubMed: 20939513DOI: 10.1021/bi101321y PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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