3N01
Crystal structure of an abridged form of the mature ectodomain of the Human Receptor-Type Protein Tyrosine Phosphatase ICA512/IA-2 at pH 8.5
Summary for 3N01
Entry DOI | 10.2210/pdb3n01/pdb |
Related | 2QT7 |
Descriptor | Receptor-type tyrosine-protein phosphatase-like N, CALCIUM ION (3 entities in total) |
Functional Keywords | ia-2, ica-512, protein-tyrosine phosphatase, transmembrane protein, diabetes, autoimmunity, proteolysis, glycoprotein, receptor, hydrolase |
Biological source | Homo sapiens (human) |
Cellular location | Membrane; Single-pass type I membrane protein: Q16849 |
Total number of polymer chains | 2 |
Total formula weight | 19315.91 |
Authors | Primo, M.E.,Jakoncic, J.,Poskus, E.,Ermacora, M.R. (deposition date: 2010-05-13, release date: 2010-11-24, Last modification date: 2023-09-06) |
Primary citation | Primo, M.E.,Jakoncic, J.,Poskus, E.,Ermacora, M.R. Receptor-type Protein-Tyrosine Phosphatase IA-2-ICA512 To be Published, |
Experimental method | X-RAY DIFFRACTION (1.3 Å) |
Structure validation
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