3MXB

Molecular basis of engineered meganuclease targeting of the endogenous human RAG1 locus

Summary for 3MXB

• Entry DOI: 10.2210/pdb3mxb/pdb
• Related: 3MX9 3MXA
• Descriptor: V3(E8K), V2(K7E-G19S), DNA (5'-D(*TP*TP*GP*TP*TP*CP*TP*CP*AP*GP*GP*TP*AP*CP*CP*TP*CP*AP*GP*CP*CP*AP*GP*A)-3'), ... (7 entities in total)
• Functional Keywords: protein-dna complex, hydrolase-dna complex, hydrolase/dna
• Biological source: Chlamydomonas reinhardtii; More
• Total number of polymer chains: 8
• Total formula weight: 109658.40

Authors

Munoz, I.G.,Prieto, J.,Subramanian, S.,Coloma, J.,Montoya, G. (deposition date: 2010-05-07, release date: 2010-10-06, Last modification date: 2024-02-21)

• Primary citation: Munoz, I.G.,Prieto, J.,Subramanian, S.,Coloma, J.,Redondo, P.,Villate, M.,Merino, N.,Marenchino, M.,D'Abramo, M.,Gervasio, F.L.,Grizot, S.,Daboussi, F.,Smith, J.,Chion-Sotinel, I.,Paques, F.,Duchateau, P.,Alibes, A.,Stricher, F.,Serrano, L.,Blanco, F.J.,Montoya, G.; Molecular basis of engineered meganuclease targeting of the endogenous human RAG1 locus.; Nucleic Acids Res., 39:729-743, 2011; PubMed: 20846960; DOI: 10.1093/nar/gkq801

Experimental method

X-RAY DIFFRACTION (2.3 Å)