3MTS

Chromo Domain of Human Histone-Lysine N-Methyltransferase SUV39H1

3MTS の概要

• エントリーDOI: 10.2210/pdb3mts/pdb
• 分子名称: Histone-lysine N-methyltransferase SUV39H1 (2 entities in total)
• 機能のキーワード: histone methyltransferase, histone-lysine n-methyltransferase, suv39h1, histone h3, tri-methylation, epigenetics, transcriptional repression, transcription regulation, chromatin, chromo domain, pre-set domain, set domain, post-set domain, structural genomics consortium, sgc, transferase
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Nucleus: O43463
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 24300.78

構造登録者

Lam, R.,Li, Z.,Wang, J.,Crombet, L.,Walker, J.R.,Ouyang, H.,Bountra, C.,Weigelt, J.,Arrowsmith, C.H.,Edwards, A.M.,Bochkarev, A.,Min, J.,Structural Genomics Consortium (SGC) (登録日: 2010-04-30, 公開日: 2010-06-30, 最終更新日: 2023-09-06)

• 主引用文献: Wang, T.,Xu, C.,Liu, Y.,Fan, K.,Li, Z.,Sun, X.,Ouyang, H.,Zhang, X.,Zhang, J.,Li, Y.,Mackenzie, F.,Min, J.,Tu, X.; Crystal Structure of the Human SUV39H1 Chromodomain and Its Recognition of Histone H3K9me2/3.; Plos One, 7:e52977-e52977, 2012; PubMed: 23285239; DOI: 10.1371/journal.pone.0052977

実験手法

X-RAY DIFFRACTION (2.2 Å)