3MRO

Crystal Structure of MHC class I HLA-A2 molecule complexed with Melan-A MART1 decapeptide variant

3MRO の概要

• エントリーDOI: 10.2210/pdb3mro/pdb
• 関連するPDBエントリー: 3GSN 3GSO 3GSQ 3GSR 3GSU 3GSV 3GSW 3GSX 3MR9 3MRB 3MRC 3MRD 3MRE 3MRF 3MRG 3MRH 3MRI 3MRJ 3MRK 3MRL 3MRM 3MRN 3MRP 3MRQ 3MRR
• 分子名称: HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, 10-meric peptide from Melanoma antigen recognized by T-cells 1, ... (4 entities in total)
• 機能のキーワード: mhc class i, hla, immune system, immune response, decapeptide, tumoral peptide, melan-a, mart1
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Membrane; Single-pass type I membrane protein: P01892; Secreted : P61769; Endoplasmic reticulum membrane; Single-pass type III membrane protein: Q16655
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 46946.30

構造登録者

Reiser, J.-B.,Le Gorrec, M.,Chouquet, A.,Debeaupuis, E.,Echasserieau, K.,Saulquin, X.,Bonneville, M.,Housset, D. (登録日: 2010-04-29, 公開日: 2011-05-25, 最終更新日: 2023-11-01)

• 主引用文献: Reiser, J.B.,Legoux, F.,Gras, S.,Trudel, E.,Chouquet, A.,Leger, A.,Le Gorrec, M.,Machillot, P.,Bonneville, M.,Saulquin, X.,Housset, D.; Analysis of Relationships between Peptide/MHC Structural Features and Naive T Cell Frequency in Humans.; J.Immunol., 193:5816-5826, 2014; PubMed: 25392532; DOI: 10.4049/jimmunol.1303084

実験手法

X-RAY DIFFRACTION (2.35 Å)