3MR2

Human DNA polymerase eta in complex with normal DNA and incoming nucleotide (Nrm)

Summary for 3MR2

• Entry DOI: 10.2210/pdb3mr2/pdb
• Related: 3MR3 3MR4 3MR5 3MR6
• Descriptor: DNA polymerase eta, DNA (5'-D(*T*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA (5'-D(*TP*AP*GP*CP*GP*TP*CP*AP*T)-3'), ... (7 entities in total)
• Functional Keywords: pol eta, polymerase, thymine dimer, cpd, xpv, xeroderma pigmentosum variant, dna damage, transferase-dna complex, transferase/dna
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus: Q9Y253
• Total number of polymer chains: 3
• Total formula weight: 56871.67

Authors

Biertumpfel, C.,Zhao, Y.,Ramon-Maiques, S.,Gregory, M.T.,Lee, J.Y.,Yang, W. (deposition date: 2010-04-28, release date: 2010-06-30, Last modification date: 2024-02-21)

• Primary citation: Biertumpfel, C.,Zhao, Y.,Kondo, Y.,Ramon-Maiques, S.,Gregory, M.,Lee, J.Y.,Masutani, C.,Lehmann, A.R.,Hanaoka, F.,Yang, W.; Structure and mechanism of human DNA polymerase eta.; Nature, 465:1044-1048, 2010; PubMed: 20577208; DOI: 10.1038/nature09196

Experimental method

X-RAY DIFFRACTION (1.83 Å)