3MQ4

Metabotropic glutamate receptor mGluR7 complexed with LY341495 antagonist

Summary for 3MQ4

• Entry DOI: 10.2210/pdb3mq4/pdb
• Related: 3ks9
• Descriptor: Metabotropic glutamate receptor 7, MAGNESIUM ION, 2-[(1S,2S)-2-carboxycyclopropyl]-3-(9H-xanthen-9-yl)-D-alanine (3 entities in total)
• Functional Keywords: glutamate receptors, mglur7, dimerization, glutamic acid binding, structural genomics, structural genomics consortium, sgc, signaling protein
• Biological source: Homo sapiens (human)
• Cellular location: Cell membrane; Multi-pass membrane protein: Q14831
• Total number of polymer chains: 1
• Total formula weight: 53990.83

Authors

Dobrovetsky, E.,Khutoreskaya, G.,Seitova, A.,He, H.,Weigelt, J.,Edwards, A.M.,Arrowsmith, C.H.,Bountra, C.,Cossar, D.,Bochkarev, A.,Structural Genomics Consortium (SGC) (deposition date: 2010-04-27, release date: 2010-06-09, Last modification date: 2024-10-30)

• Primary citation: Dobrovetsky, E.,Khutoreskaya, G.,Seitova, A.,He, H.,Edwards, A.M.,Arrowsmith, C.H.,Bountra, C.,Weigelt, J.,Cossar, D.,Bochkarev, A.; mGluR7 complexed with LY341495; To be Published,

Experimental method

X-RAY DIFFRACTION (2.8 Å)