3MPH

The structure of human diamine oxidase complexed with an inhibitor aminoguanidine

3MPH の概要

• エントリーDOI: 10.2210/pdb3mph/pdb
• 関連するPDBエントリー: 3HI7 3HIG 3HII 3K5T
• 分子名称: Amiloride-sensitive amine oxidase, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• 機能のキーワード: oxidoreductase, copper amine oxidase, cao, topaquinone, tpq, diamine oxidase, dao, human, aminoguanidine
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 170035.68

構造登録者

McGrath, A.P.,Guss, J.M. (登録日: 2010-04-27, 公開日: 2010-09-08, 最終更新日: 2023-11-01)

• 主引用文献: McGrath, A.P.,Caradoc-Davies, T.,Collyer, C.A.,Guss, J.M.; Correlation of active site metal content in human diamine oxidase with trihydroxyphenylalanine quinone cofactor biogenesis; Biochemistry, 49:8316-8324, 2010; PubMed: 20722416; DOI: 10.1021/bi1010915

実験手法

X-RAY DIFFRACTION (2.05 Å)