3MP2

Crystal structure of transmissible gastroenteritis virus papain-like protease 1

Summary for 3MP2

DescriptorNon-structural protein 3, ZINC ION (3 entities in total)
Functional Keywordspapain-like protease, tgev, coronavirus, hydrolase
Biological sourcePorcine transmissible gastroenteritis coronavirus (TGEV)
Cellular locationNon-structural protein 3: Host membrane; Multi-pass membrane protein (Potential). Non-structural protein 4: Host membrane; Multi-pass membrane protein (Potential). Non-structural protein 6: Host membrane; Multi-pass membrane protein (Potential). Non-structural protein 7: Host cytoplasm, host perinuclear region (By similarity). Non-structural protein 8: Host cytoplasm, host perinuclear region (By similarity). Non-structural protein 9: Host cytoplasm, host perinuclear region (By similarity). Non-structural protein 10: Host cytoplasm, host perinuclear region (By similarity) P0C6V2
Total number of polymer chains1
Total molecular weight23656.64
Authors
Wojdyla, J.A.,Manolaridis, I.,Tucker, P.A. (deposition date: 2010-04-24, release date: 2010-09-08, Last modification date: 2011-07-13)
Primary citation
Wojdyla, J.A.,Manolaridis, I.,van Kasteren, P.B.,Kikkert, M.,Snijder, E.J.,Gorbalenya, A.E.,Tucker, P.A.
Papain-Like Protease 1 from Transmissible Gastroenteritis Virus: Crystal Structure and Enzymatic Activity toward Viral and Cellular Substrates.
J.Virol., 84:10063-10073, 2010
PubMed: 20668092 (PDB entries with the same primary citation)
DOI: 10.1128/JVI.00898-10
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.5 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.222803.9%2.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution