3MOB
Crystal structure of the neutralizing HIV antibody 2F5 Fab fragment (recombinantly produced Fab) with 11 aa gp41 MPER-derived peptide
Summary for 3MOB
Entry DOI | 10.2210/pdb3mob/pdb |
Related | 1TJH 3MNV 3MNW 3MNZ 3MO1 3MOA 3MOD |
Descriptor | gp41 MPER-derived peptide, ANTI-HIV-1 ANTIBODY 2F5 LIGHT CHAIN, ANTI-HIV-1 ANTIBODY 2F5 HEAVY CHAIN, ... (4 entities in total) |
Functional Keywords | hiv-1, hiv gp41 mper, 13h11, 2f5, z13, 4e10, fab antibody, immune system |
Biological source | Homo sapiens (mouse,human) More |
Total number of polymer chains | 3 |
Total formula weight | 49936.18 |
Authors | Nicely, N.I.,Dennison, S.M.,Kelsoe, G.,Liao, H.-X.,Alam, S.M.,Haynes, B.F. (deposition date: 2010-04-22, release date: 2010-11-17, Last modification date: 2023-09-06) |
Primary citation | Nicely, N.I.,Dennison, S.M.,Kelsoe, G.,Ueda, Y.,Liao, H.-X.,Alam, S.M.,Haynes, B.F. Crystal Structure of a Non-Neutralizing HIV-1 gp41 Envelope Antibody Demonstrates Neutralization Mechanism of gp41 Antibodies To be Published, |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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